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The 50 mg dose is both a starting dose and the therapeutic dose Pristiq or the generic Desvenlafaxine Succinate is an antidepressant that belongs to a class of drugs called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). Pristiq is a brand-name prescription drug that’s used to treat major depressive disorder (MDD) in adults. [2] It is recommended that the need for further treatment be occasionally reassessed. Medical Information Page - clinical & safety information, ways to contact Pfizer Medical & other resources. Pristiq Dosage and Administration General Instructions for Use The recommended dose for Pristiq is 50 mg once daily, with or without food. Ca to learn more about our payment assistance. Medication Guide ; for Healthcare professionals: PRISTIQ U. Payment Assistance ProgramAdditionally, Canadians may consult www. 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